- Born: Cir 1222, Duston, Northamptonshire, England 1687
- Marriage (1): Sir Walter De Grey of Rotherfield
- Died: 1304, Rotherfield, East Sussex, England about age 82 1428,1688
Isabel married Sir Walter De Grey of Rotherfield, son of Robert De Grey of Rotherfield and Beatrice de Sculcotes. (Sir Walter De Grey of Rotherfield was born about 1222 in Rotherfield, Somerton and Hardwick, Oxfordshire, England and died before 12 Jan 1267 in Upton in Badsworth, Yorkshire, England.)
Noted events in their marriage were:
• Wardship of Isabel. 1689 The Archbishop had been granted the wardship of William Duston's daughters and coheirs, and married two of them to his nephews - Walter de Grey, married to Isabel Duston, and John d'Oyley married to Rose Duston.(Calendar of Inquisitions Post Mortem, Vol.1, no. 760; Pipe Roll 6 Henry III, p.214-215).